What You Should Know About Your Diet and Warfarin What is warfarin.Warfarin is an anticoagulant medication that is used to slow down the blood-clotting process.Patients are confused by alternating daily doses (e.g. 7.5 and 5.0 mg).

Warfarin Fluoroquinolones Antiepileptic Drugs Lithium Oral Contraceptives Cisapride Sildenafil 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors Selective Serotonin Reuptake Inhibitors Sources of Information on Drug Interactions References Sildenafil (Viagra) is the first oral medication labeled by the U.S. Food and Drug Administration for the treatment of erectile dysfunction.Warfarin is an anticoagulant drug that is also known under the brand names of Coumadin, Jantoven, Marevan, Lawarin and Waran.

Comparison of Warfarin and Aspirin for Symptomatic

Concomitant use of statins and erythromycin, itraconazole, niacin or gemfibrozil (Lopid) can cause toxicity that manifests as elevated serum transaminase levels, myopathy, rhabdomyolysis and acute renal failure. 19 Used alone, any statin can cause these adverse effects.

Warfarin (brand names Coumadin and Jantoven) is a prescription medication used to prevent harmful blood clots from forming or growing larger.Consumer information about the medication WARFARIN - ORAL (Coumadin), includes side effects, drug interactions, recommended dosages, and storage information. Read.Cisapride (Propulsid) plus erythromycin, clarithromycin, fluconazole, itraconazole (Sporanox), ketoconazole (Nizoral), nefazodone (Serzone), indinavir (Crixivan) or ritonavir (Norvir) Prolongation of QT interval along with arrhythmias secondary to inhibited cisapride metabolism Generally within 1 week Avoid.Warfarin (Coumadin, Jantoven) is a prescription drug used to treat DVTs, reduction of pulmonary embolism and atrial fibrillation, and prevent strokes and heart attacks.Oral contraceptive pills plus rifampin Decreased effectiveness of oral contraception Any time Avoid if possible.Significant changes in INR can usually be achieved by small changes in dose (15% or less).Find patient medical information for Warfarin Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.Concomitant use of rifampin and oral contraceptive pills can lead to breakthrough bleeding and an increased risk of pregnancy.Creatine kinase levels should be measured if these symptoms occur.

Comparison of Warfarin and Aspirin for Symptomatic Intracranial Arterial Stenosis Marc I.Although concomitant use of gemfibrozil or niacin with an HMG-CoA reductase inhibitor may appear clinically appropriate, these combinations have been associated with a 2 to 5 percent increase in the risk of myopathy. 21 Case reports describing these interactions are questionable because gemfibrozil and niacin have independently been associated with myopathy.

Management and Dosing of Warfarin Therapy

SSRI plus selegiline (Eldepryl) or nonselective monoamine oxidase inhibitor Hypertensive crisis Soon after initiation Avoid.

Coumadin (warfarin) is a cheap and effective medicine that prevents new blood clots.One retrospective study found that the risk of hemorrhagic peptic ulcers was 13 times greater in patients older than 65 years who were taking NSAIDs and warfarin than in patients of the same age who were taking neither drug. 10 If NSAID therapy is necessary, a cyclooxygenase-2 inhibitor should be used, and the INR should be closely monitored.As a result, many physicians feel overwhelmed and question the safety of multiple drug regimens.

Annotation of CPIC Guideline for warfarin and CYP2C9

T o p 1 0 L i s t o f S a f e t y T i p s f o r W a r f a r i n Brought to you by the Institute for Safe Medication Practices Warfarin C O U M A DI N C O U M AD I N.

Minimize changes in intake of green leafy vegetables (spinach, greens, and broccoli), green peas, and oriental green tea.Combining a cytochrome P450 inhibitor with a substrate can potentiate the pharmacologic effects of the substrate.


Possible Interactions with: Vitamin K | University of

TABLE 1 Overview of Selected Serious Drug Interactions Interaction Potential effect Time to effect Recommendations and comments Warfarin (Coumadin) plus ciprofloxacin (Cipro), clarithromycin (Biaxin), erythromycin, metronidazole (Flagyl) or trimethoprim-sulfamethoxazole (Bactrim, Septra) Increased effect of warfarin Generally within 1 week Select alternative antibiotic.Yet another report on 14 patients discovered no significant interaction between SSRIs and sumatriptan. 31 The authors concluded that the combination may be safe.Recognizing drug interactions is a daily challenge for family physicians, and remembering all potential interactions has become virtually impossible.Lithium plus NSAID or diuretic Increased lithium levels Any time Decrease lithium dosage by 50% and monitor lithium levels.

A comparison of aspirin with placebo in patients treated with warfarin after heart-valve replacement.TRADE OR OTHER NAMES The active ingredient warfarin is found in a variety of commercial rodenticides.

side effects of warfarin - DVT deep vein thrombosis forum

TRIPTANS A recent report documented six cases of serotonin syndrome in patients taking fluoxetine and sumatriptan (Imitrex). 29 The authors of the report suggested that this drug combination should be used with caution.

Warfarin - FPnotebook.com

Hershey Medical Center, Pennsylvania State University, Hershey, Pa.A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference.

It is prescribed for people with certain types of irregular.This page includes the following topics and synonyms: Warfarin, Coumadin, Anticoagulation after Heart Valve Replacement, Valve Replacement and Anticoagulation.Now you can view all dosing information on your mobile device.SSRI plus naratriptan (Amerge), rizatriptan (Mazalt), sumatriptan (Imitrex) or zolmitriptan (Zomig) Serotonin syndrome Possibly after initial dose Avoid if possible.Patients taking warfarin should eat a diet that is constant in vitamin K.As use of this over-the-counter product increases, more data supporting clinically significant drug interactions should become available.Signs or symptoms of lithium toxicity involve the central nervous system (drowsiness, confusion, hand tremor, blurred vision, vertigo and seizures), gastrointestinal tract (nausea and vomiting) and cardiovascular system (arrhythmias and widening of the QRS complex).Cisapride plus class IA or class III antiarrhythmic agents, tricyclic antidepressants or phenothiazine Prolongation of QT interval along with arrhythmias Any time Avoid.

Drugs that inhibit this enzyme, including erythromycin, cimetidine, ketoconazole and itraconazole, may increase plasma sildenafil concentrations.If either combination is used, patients should be alert for muscle pain, tenderness or weakness.

Warfarin Fluoroquinolones Antiepileptic Drugs Lithium Oral Contraceptives Cisapride Sildenafil 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors Selective Serotonin Reuptake Inhibitors Sources of Information on Drug Interactions References ANTIBIOTICS Because of new clinical recommendations, the use of warfarin (Coumadin) has increased in recent years.Warfarin is an oral medication used to treat clots in the heart, lower body, and the lungs.If combination therapy is necessary, recommend use of alternative contraceptive method during cycle.